Some of the drugs used to treat HIV patients are competitive inhibitors of the HIV reverse transcriptase enzyme. Unfortunately, the high mutation rate of HIV means that the virus rapidly acquires mutations with amino acid changes that make them resistant to these competitive inhibitors. Where in the reverse transcriptase enzyme would such amino acid changes most likely occur in drug-resistant viruses?

Some of the drugs used to treat HIV patients are competitive inhibitors of the HIV reverse transcriptase enzyme. Unfortunately, the high mutation rate of HIV means that the virus rapidly acquires mutations with amino acid changes that make them resistant to these competitive inhibitors. Where in the reverse transcriptase enzyme would such amino acid changes most likely occur in drug-resistant viruses? 





A) in or near the active site
B) at an allosteric site
C) at a cofactor binding site
D) in regions of the protein that determine packaging into the virus capsid
E) such mutations could occur anywhere with equal probability






Answer: A


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9 comments

russell robertson...
There has been progress in herbal medicine of DR AKHIGBE which have become safer,in curing diseases;i was suffering and dying of herpes for past two years,untill i came across DR AKHIGBE on internet i email him on drrealakhigbe@gmail.com 'glory be to GOD'am cured of herpes by drinking his herbal medicine cure [HMC] he sent to me. Herbal medicine cure have made it possible curing diseases. i was once a victim and am giving out a living testimonies , and am been restore.
So become easier to take or drink and where early herbal often required drinking it as frequently as 3 to 5 times per day, most first-line cured, herbal medicine now comprise a single daily fixed taking as the instruction followed. DR AKHIGBE also cure others diseases like ; HIV/AIDS,DIABETES,CANCER,HERPES,SYPHILLIS,MENINGITES,GENITAL AND SIMPLEX HERPES, ALS,HEPATITES A AND B.etc any one out there been effected by diseases to email drrealakhigbe@gmail.com or whatApp him on +2348142454860. GET YOUR HERBAL AND GET YOUR FREEDOM.


So is possible that HIV Disease can be cured because i have been scammed so many times not until i came across this great man dr akhigbe who helped me at first I never believe all this comment and post about him and I was very sick because i have been infected with HIV Disease for the past two year,just last 2months I keep reading the testimony about this man named dr akhigbe they said that the man is so powerful he have cured different type of diseases, I keep monitor the post of some people about this man and I found out that he was real so i decided to give him a trial I contacted him for help and he said he was going to help me get my cure that all i needed to do was to send him money to prepare the medication after which it will be sent to me via dhl service which i did to my greatest surprise the medication was sent to me he gave me instructions on how to use it that after three weeks i should go for check up,after taking the medicine and follow his instruction after three weeks i went back to the hospital for another test, at first i was shocked when the doctor told me that i was negative i ask the doctor to check again and the result was still the same negative that was how i free from HIV Disease at of the shock i decided to come and share my own testimony with you for those who think there is no cure for HIV Disease the cure as finally come' stop doubting and contact dr akhigbe via email drrealakhigbe@gmail.com he will help you out you can also wattssap him via +2348142454860 he is also perfect in curing DIABETICS,HERPES,HIV/AIDS, ;ALS, CANCER HEPATITIES A AND B, believe me that deadly disease is not longer a deadly sentence becauase dr akhigbe has the cure.the godfather of herbalism.

God bless Dr.okosun for his marvelous work in my life, I was diagnosed of HIV since 2015 and I was taking my medications, I wasn't satisfied i needed to get the HIV out of my system, I searched about some possible cure for HIV i saw a comment abou how he cured HIV with his herbal medicine, I contacted him and he guided me. I asked for solutions, he started the remedy for my health, he sent me the medicine through UPS SPEED POST. I took the medicine as prescribed by him and 5days later i was cured from HIV, Dr.okosun truly you are great, do you need his help also? Why don't you contact him through you can also reach him on phone:+2347060571038 or hem On that very email dr.okosunspellalter@gmail.com
whatsup :+2347060571038
DOCTOR okosun, CAN AS WELL CURE THE FOLLOWING DISEASE:-

1. HIV/AIDS
2. HERPES
3. CANCER
4. ALS (5) enlarge penis

God bless Dr.okosun for his marvelous work in my life, I was diagnosed of HIV since 2015 and I was taking my medications, I wasn't satisfied i needed to get the HIV out of my system, I searched about some possible cure for HIV i saw a comment abou how he cured HIV with his herbal medicine, I contacted him and he guided me. I asked for solutions, he started the remedy for my health, he sent me the medicine through UPS SPEED POST. I took the medicine as prescribed by him and 5days later i was cured from HIV, Dr.okosun truly you are great, do you need his help also? Why don't you contact him through you can also reach him on phone:+2347060571038 or hem On that very email dr.okosunspellalter@gmail.com
whatsup :+2347060571038
DOCTOR okosun, CAN AS WELL CURE THE FOLLOWING DISEASE:-

1. HIV/AIDS
2. HERPES
3. CANCER
4. ALS (5) enlarge penis

I find something in herbal medicine good to share on here with anyone suffering from the disease such as HIV, Herpes, Hepatitis or Chronic Lyme Disease, Lupus as well.Dr Itua herbal made cure my HIV and gave me hope that he can cure all types of diseases I believed him) I do the best of myself that I can do, I went for a program in west Africa about fashion on another side I was HIV positive. I walk through a nearby village for our program schedule then I found a signage notice that says Dr Itua Herbal Center then I asked my colleagues what all about this very man called Dr Itua, She told me that he's a herbal doctor and he can cure all kind of disease i walked to him and explain myself to him as I'm a strangler out there he prepared me herbal medicine and told me how to drink it for two weeks, when I get to my hotel room I take a look at it then says a prayer before I drank it not knowing after two weeks I went to test and I found out I was negative I ran to him to pay him more but he refuses and says I should share his works for me around the globe so sick people can see as well. I'm writing a lot about him this season so that is how I was cured by drinking Dr Itua herbal medicine, He's A caring man with godly heart. Well - everything I decided all go through for me well and how you're going to treat this new aspect to your life. You don't have to suffer alone, and it's okay to ask for help. It also doesn't have to be a constant demon, as you'll get to know your body and yourself in a much deeper way than most people. Take advantage of this, as it will help you appreciate Africa Herbal Made.
Dr Itua Contact Information.
Email...drituaherbalcenter@gmail.com
Whatsapp Number....+2348149277967

Hello everyone, i am here today on this forum giving a life testimony on how I was cured from HIV Virus while this may sound discouraging and people may not be-live that HIV CURE has be found,while i was once an HIV positive i live with this disease for more than years now, i have been to so many places for help including hospitals wasted money and times hoping that i was going to get cure but nor was able, until God use someone to cure me from this disease (HIV) true the help of a man called Dr osemu with his herbal root herbs medicine. while i don’t have much to say but to give thanks and praise to God almighty who use Sir Dr osemu to extend my life for what you have done for me DR, i will not stop thanking you because you put a smile on my face again.thanks once again if you are into similar problem or with any kind of diseases you can contact Sir Dr osemu on his mail drosemusolutionhome@gmail.com or call him or whatsapp  on +2348108356068and i will not stop thanking you DR osemu for what you have done for me in my life, i will keep posting to the world for them to no that you are in existence , thanks for your audience and i hope you find help like i did for what he has done for me, if you are into similar problem like HERPES,HEPATITIS B,CANCER,DIABETICS.do not wast time to contact him now his WhatsApp +2348108356068 and his email drosemusolutionhome@gmail.com.

It was a wonderful experience knowing Dr James.
I had a sudden onset of cold sores and a new one was appearing each day. I'm on primary immunosuppressant I noticed my body just can't fight this virus on its own. After five days of treatment and no success I suspected herpes I went for test and it was confirmed. I knew I was in trouble as I've already lost appetite for everything about life I've heard of people who suffered this disease for years with no hope of solution. Imagine the pain and trauma keeping it a secret. God was my strength I met a doctor for treatment who after telling him of my ailment he advised me to start with herbal medicines if I wish to live longer than doctors estimate He taught me the strong effects of plants on animals and how possible nature have perfected itself. He gave me Dr James herbal mix contact. I contacted him immediately, I told him the whole history which he gave me satisfactory answer. I purchased and started using his herbs as he had directed. This medication was far amazing that within 24-48 hrs the blisters were crusting over. The swelling and redness was decreasing as well. I continued on dosage as prescribed one week later I noticed total comfort in my body system, I informed the doctor who advised me to continue medication till later end I was on four weeks herpes medication which I completed before going for test. I went for herpes test and then again back to my doctor who confirmed me herpes negative it was really like a dream. What a relief! I thank you greatly Dr  James for giving me back my life I'm the happiest man on earth. Reach Dr James  directly via email: drjamesherbalmix@gmail.com.Or Whatsapp Him on his mobile  +2348152855846  TO CURE YOUR DISEASES WITH HERBAL MEDICINES  

I'm here to give my testimony how I was cured from HIV, I contacted my HIV via blade. A friend of my use blade to peel of her finger nails and drop it where she use it, so after she has left i did know what came unto me i looked at my nails, my nails were very long and I took the blade which she just used on her own nails to cut of my finger nails, as i was maintaining my names, i mistakenly injured myself. I did even bother about it, so when I got to the hospital the next week when i was ill the doctor told me that I am HIV positive, i wondered where did i got it from so i remembered how I use my friend blade to cut off my hand so i feel so sad in my heart to the extent that i don’t even know what to do, so one day i was passing through the internet i met a testimony of a lady that all talk about how she was cured by a doctor called DR Imoloa so i quickly emailed the doctor and he also replied to me and told me the requirements which i will provide and I do according to his command, he prepare a herbal medicine for me which I took. He message me the following week that i should go for a test which i did to my own surprise i found that i was HIV negative. He also have cured for all kinds of incurable diseases like: Huntington's disease, back acne, chronic kidney failure, Addison's disease, Chronic Disease, Crohn's Disease, Cystic Fibrosis, Fibromyalgia, Inflammatory Bowel Disease, Fungal Nail Disease, Paralysis, Celia Disease , Lymphoma, Major Depression, Malignant Melanoma, Mania, Melorheostosis, Meniere's Disease, Mucopolysaccharidosis, Multiple Sclerosis, Muscle Dystrophy, Rheumatoid Arthritis, Alzheimer Disease and so many. Thanks to him once more the great doctor that cured me dr. Imoloa so you can also email him via drimolaherbalmademedicine@gmail.com or what'sapp him on +2347081986098.. God Bless you Sir.

I Never believed i was ever going to be HSV FREE again, DR.Ehiaguna has given me reasons to be happy, i was HSV positive for 2 years and all the means and medicine i tried for treatment was not helpful to me, but when i came on the Internet i saw great testimony about DR.Ehiaguna on how he was able to cure someone from HSV 2, this person said great things about this man, and advice we contact him for any Disease problem that DR.Ehiaguna can be of help, well i decided to give him a try, he requested for my information which i sent to him, and he told me he was going to prepare for me a healing portion, which he wanted me to take for days, and after which i should go back to the hospital for check up, well after taking all the treatment sent to me by DR.Ehiahuna , i went back to the Hospital for check up, and now i have been confirmed HSV NEGATIVE, friends you can reach DR.Ehiaguna on any treatment of any Disease cos i saw many testimony of different disease like, HEPATITIS,HIV AIDS,EPILEPSY, CANCER,CFS he is the one only one i can show you all up to, reach him on drehiaguna@gmail.com or whatsApp him now +2348073908953. quick contact him for help and you can just quickly drop your number on your first mail as i did for easily conversation